
| Planning, Construction, and Statistical Analysis of Comparative Experiments Wiley Series in Probability and Statistics Author: Francis G. Giesbrecht Publisher: Wiley-Interscience Publication Date: 2004-04-01 Number Of Pages: 693 At once a comprehensive handbook for the active researcher and a thorough introduction for the advanced student, this reference provides * Coverage of wide range of applications, including agricultural sciences, animal and biomedi-cal sciences, and industrial and engineering studies * Information on new developments in the design of fractional factorials with non-prime numbers of levels in mixed-level fractional factorials * Detailed information on the construction of plans and the relationships among categories of designs * Thorough discussion of balanced, partially balanced, lattice, cyclic and alpha-designs * Accommodations for how to evaluate the power and efficiency of designs that are not perfectly balanced * Unified and simplified presentation of general forms for estimation and hypothesis testing ~ Pharmaceutical Experimental Design (Drugs & the Pharmaceutical Sciences) (Drugs and the Pharmaceutical Sciences: a Series of Textbooks and Monographs) Author: Gareth A. Lewis Publisher: Marcel Dekker Publication Date: 1998-09-01 Number Of Pages: 512 This useful reference describes the statistical planning and design of pharmaceutical experiments, covering all stages in the development process-including preformulation, formulation, process study and optimization, scale-up, and robust process and formulation development.Shows how to overcome pharmaceutical, technological, and economic constraints on experiment design!Directly comparing the advantages and disadvantages of specific techniques, Pharmaceutical Experimental Designoffers broad, detailed, up-to-date descriptions of designs and methods not easily accessible in other booksreviews screening designs for qualitative factors at different levelspresents designs for predictive models and their use in optimizationhighlights optimization methods, such as steepest ascent, optimum path, canonical analysis, graphical analysis, and desirabilitydiscusses the Taguchi method for quality assurance and approaches for robust scaling up and process transferdetails nonstandard designs and mixturesanalyzes factorial, D-optimal design, and offline quality assurance techniquesreveals how one experimental design evolves from anotherand more!Featuring over 700 references, tables, equations, and drawings, Pharmaceutical Experimental Design is suitable for industrial, research, and clinical pharmaceutical scientists, pharmacists, and pharmacologists; statisticians and biostatisticians; drug regulatory affairs personnel; biotechnologists; formulation, analytical, and synthetic chemists and engineers, quality assurance personnel; all users of statistical experimental design in research and development; and postgraduate and postdoctoral research workers in these disciplines ~ Oxford Handbook of Clinical and Laboratory Investigation (Oxford Handbooks Series) Author Publisher: Oxford University Press, USA Publication Date: 2003-01-23 Number Of Pages: 622 Modern medicine is highly complex and investigations are a key part of the diagnostic process. With major advances in technology there are thousands of clinical and laboratory tests available. The 'Oxford Handbook of Clinical & Laboratory Investigation' provides a patient-oriented approach to investigation where key symptoms and signs are described along with tests that may be of value in reaching a diagnosis. The remainder of the Handbook is specialty-centered and provides a comprehensive review of all available tests within a given subject. Contributors are all active clinicians who are engaged in medical practice, who appreciate the problems faced by junior doctors. The Handbook should also be of value to senior medical students, and who will soon be on the wards and responsible for ordering tests on their patients ~ Applied Optimal Designs Author: Martijn P.F. Berger Publisher: John Wiley & Sons Publication Date: 2005-03-25 Number Of Pages: 312 There is an increasing need to rein in the cost of scientific study without sacrificing accuracy in statistical inference. Optimal design is the judicious allocation of resources to achieve the objectives of studies using minimal cost via careful statistical planning. Researchers and practitioners in various fields of applied science are now beginning to recognize the advantages and potential of optimal experimental design. Applied Optimal Designs is the first book to catalogue the application of optimal design to real problems, documenting its widespread use across disciplines as diverse as drug development, education and ground water modelling. Includes contributions covering -Bayesian design for measuring cerebral blood-flow -Optimal designs for biological models -Computer adaptive testing -Ground water modelling -Epidemiological studies and pharmacological models Applied Optimal Designs bridges the gap between theory and practice, drawing together a selection of incisive articles from reputed collaborators. Broad in scope and inter-disciplinary in appeal, this book highlights the variety of opportunities available through the use of optimal design. The wide range of applications presented here should appeal to statisticians working with optimal designs, and to practitioners new to the theory and concepts involved ~ Nanofabrication Towards Biomedical Applications Overall, the editors and authors have done a good job, resulting in a book that can be read with interest by the broad scientific community. This book deserves a respected place on the desk of the student, the professor, and the engineer, who will all benefit equally from reading it." (Angewandte Chemie I.E.) "The book will definitely be of interest not only to readers with biological and medical backgrounds but also to material scientists, engineers, chemists, and physicists. The last two chapters are highly recommended for the general public and even politicians who are interested in looking at global changes arising from the implementation of nano- and biotechnology." (Small) "...this is an excellent and useful reference book about biomedical nanotechnology." (Advanced Materials) Book Description This book focuses on the materials, synthetic methods, tools and techniques being developed in the nanoregime towards the life sciences -- in particular biology, biotechnology and medicine. Readers from materials science, engineering, chemistry, biology and medical backgrounds will find detailed accounts of the design and synthesis of nanomaterials and the tools and techniques involved in their production for applications in biology, biotechnology and medicine ~ Biomedical Applications of Polyurethanes (Tissue Engineering Intelligence Unit) Book Properties ISBN: 158706023X Author: Patrick Vermette Publisher: Landes Bioscience Publication Date: 2001-08-21 Number Of Pages: 272 Average Amazon Rating Editorial Description The authors of this book discuss polyurethanes used in a variety of biomedical applications. Polyurethanes form a large family of polymeric materials with an enormous diversity of chemical compositions and properties The wide range of properties that can be achieved with polyurethane chemistry has attracted the attention of developers of biomedical devices who see promise in the mechanical flexibility of these materials combined with their high tear strength ~ E. coli in Motion Biological and Medical Physics, Biomedical Engineering ISBN: 0387008888 Author: Howard C. Berg Publisher: Springer Edition: 1 edition (October 1, 2003) Hardcover: 134 pages URL: /http://www.amazon.com/exec/obidos/redirect?tag=songstech-20&path=ASIN%2F0387008888 Summary: The bacterium Escherichia coli – E. coli for short – has long been the organism of choice for unraveling biochemical pathways, deciphering the genetic code, learning how DNA is replicated and read, and even for manufacturing proteins of commercial interest. For some thirty years, it also has been a model for studying the molecular biology of behavior. E. coli swims in a purposeful manner, propelled by long thin helical filaments, each driven at its base by a reversible rotary engine. As a microscopic organism immersed in an aqueous environment, it has mastered physical constraints utterly different from any that we know, devising sensors, comparators, and motors on the nanometer scale. This cross-disciplinary monograph describes these feats in a manner accessible to scientists, engineers, and others not trained in microbiology who would like to learn more about living machines. It treats the history of the subject, the physiology, physics, biochemistry and genetics, largely from first principles. It is all about a small but remarkably sophisticated friend who lives in your gut. Topics discussed include: How does E. coli move about? How do cells decide whether life is getting better or worse? What is the machinery that makes this behavior possible? How is the construction of this machinery programmed? How does this machinery work? What remains to be discovered ~ Recent Progress of Biochemical and Biomedical Engineering in Japan II Book Properties ISBN: 3540204199 Author: Takeshi Kobayashi Publisher: Springer Publication Date: 2004-08-26 Number Of Pages: 224 Average Amazon Rating Editorial Description The areas we deal with in biochemical engineering have expanded to include many various organisms and humans. This book has gathered together the information of these expanded areas in biochemical engineering in Japan. These two volumes are composed of 15 chapters on microbial cultivation techniques, metabolic engineering, recombinant protein production by transgenic avian cells to biomedical engineering including tissue engineering and cancer therapy. Hopefully, these volumes will give readers ~ Biomedical Engineering Handbook, Volume I Book Properties ISBN: 084930461X Author: Joseph D. Bronzino Publisher: CRC Press Publication Date: 1999-12-28 Number Of Pages: 1656 Average Amazon Rating: 4.5 Editorial Description Called the "Bible of biomedical engineering," the new edition of this bestselling handbook continues to define the field of biomedical engineering and provide a comprehensive overview of the specific fields of activity it encompasses. This edition represents a major revision that incorporates the technological changes emerging since publication of the first edition in 1995 and reflects the growth and innovations in this dynamic discipline. It includes important new sections, such as Biomimetrics ~ Image Processing : Principles and Applications Hardcover: 448 pages Publisher: Wiley-Interscience (September 8, 2005) Language: English ISBN: 0471719986 Format: PDF Pages: 451 Image processing-from basics to advanced applications Learn how to master image processing and compression with this outstanding state-of-the-art reference. From fundamentals to sophisticated applications, Image Processing: Principles and Applications covers multiple topics and provides a fresh perspective on future directions and innovations in the field, including: Image transformation techniques, including wavelet transformation and developments Image enhancement and restoration, including noise modeling and filtering Segmentation schemes, and classification and recognition of objects Texture and shape analysis techniques Fuzzy set theoretical approaches in image processing, neural networks, etc. *******-based image retrieval and image mining Biomedical image analysis and interpretation, including biometric algorithms such as face recognition and signature verification Remotely sensed images and their applications Principles and applications of dynamic scene analysis and moving object detection and tracking Fundamentals of image compression, including the JPEG standard and the new JPEG2000 standard Additional features include problems and solutions with each chapter to help you apply the theory and techniques, as well as bibliographies for researching specialized topics. With its extensive use of examples and illustrative figures, this is a superior title for students and practitioners in computer science, wireless and multimedia communications, and engineering. Review The applications for image processing technology are increasing rapidly as computers become more powerful. Images enable a doctor to view the inside of the body in a manner that gives him useful information he could never decipher out of the raw data. With the increase in the demand for images, so has the need for information on digital image processing. This book begins with the image sensor and continues through the programming techniques that are applicable . This includes both processing the image for automatic analysis (fingerprint or facial feature analysis), or presenting the image for human evaluation (a digital camera). The book is primarily interested in still images rather than video. The early chapters in the book are oriented to the basic technology of image processing that are used in virtually all applications. This includes a chapter on color imagry and others on the mathematical tranforms. Later chapters are broken down more to application areas such as biomedical, and satellite sensors and imageries. Finally the last chapters discuss image compression to minimize image storage space and transmission times. This includes a full discussion on the new JPEG 2000 standard. One of the authors, Dr. Acharya was a member of the committee developing this standard. This book is suitable for use as a text in a formal setting, or for the individual who may be interested ~ Biological Nanostructures and Applications of Nanostructures in Biology : Electrical, Mechanical, and Optical Properties Bioelectric Engineering Summary Biological Nanostructures and Applications of Nanostructures in Biology: Electrical, Mechanical, and Optical Properties contains reviews and discussions of contemporary and relevant topics dealing with the interface between the science and technology of nanostructures and the science of biology. Moreover, this book supplements these past groundbreaking discoveries with discussions of promising new avenues of research that reveal the enormous potential of emerging approaches in nanobiotechnology. The topics include - Biomedical applications of semiconductor quantum dots, - Integrating and tagging biological structures with nanoscale quantum dots, - Applications of carbon nanotubes in bioengineering, - Nanophysical properties of living cells, - Bridging natural nanotubes with fabricated nanotubes, - Bioinspired approaches to building nanoscale devices and systems, - Hairpin formation in polynucleotides. This state-of-the-art survey of key developments in nanotechnology - as they apply to bioengineering and biology - is essential reading for all academics, biomedical engineers, medical physicists, and industry professionals wishing to take advantage of the latest developments and highly-promising discoveries in nanoscience underlying applications in bioengineering and biology ~ Handbook of Medical Imaging: Processing and Analysis Biomedical Engineering Summary In recent years, the remarkable advances in medical imaging instruments have increased their use considerably for diagnostics as well as planning and follow-up of treatment. Emerging from the fields of radiology, medical physics and engineering, medical imaging no longer simply deals with the technology and interpretation of radiographic images. The limitless possibilities presented by computer science and technology, coupled with engineering advances in signal processing, optics and nuclear medicine have created the vastly expanded field of medical imaging. The Handbook of Medical Imaging is the first comprehensive compilation of the concepts and techniques used to analyze and manipulate medical images after they have been generated or digitized. The Handbook is organized in six sections that relate to the main functions needed for processing: enhancement, segmentation, quantification, registration, visualization as well as compression storage and telemedicine. * Internationally renowned authors(Johns Hopkins, Harvard, UCLA, Yale, Columbia, UCSF) * Includes imaging and visualization Contains over 60 pages of stunning, four-color images ~ Textbook of Clinical Trials A comprehensive volume on clinical trials that covers all important disease and therapeutic areas together with methodologies, phase I/II/III studies and other issues. The volume catalogues the impact of clinical trials on the practice of medicine and discusses the developments and practice of medical statistics. Cancer, cardiovascular disease, dermatological, dental, mental, ophthalmic health, gynaecology and respiratory diseases are all discussed in separate chapters, with discussions on outcome measures, competing risks and statistical models given for each therapy area. It also presents: * A history of clinical trials * A summary of pertinent statistical issues * How to choose a clinical trial design * Ethical constraints and considerations * Clinical trial issues in paediatrics and those involving older patients * Clinical trials in complementary medicine ~ Essentials Dental Radiography and Radiology Review "This book continues to be an excellent publication and one which many people will wish to have on their shelves and in their libraries." L. Brocklebank, British Dental Journal, January 2003 Book Description This is a third edition of the dominant textbook in this field, which is used in nearly all dental schools in the UK and in many other countries. Covers both radiography (producing the image) and radiology (interpreting the image) and presents the subject in an accessible format. This new edition has been revised in accordance with important new guidelines on radiation protection which came into force in January 2000. Product Details * Paperback: 448 pages * Publisher: Churchill Livingstone; 3 edition (June 15, 2002) * Language: English * ISBN: 044307027X * Format: PDF * Size: 48.7 MB * Price: $73.95 ~ Introduction to Medical Electronics Applications Summary Medical electronics, or more specifically the instrumentation used in physiological measurement, has changed significantly over the last few years. Developments in electronics technology have offered new and enhanced applications, especially in the areas of data recording and analysis and imaging technology. These changes have been accompanied by more stringent legislation on safety and liability. This book is designed to meet the needs of students on the growing number of courses, undergraduate and MSc. It is a concise and accessible introduction offering a broad overview that encompasses the various contributing disciplines. ~ The Measurement Instrumentation and Sensors Handbook ISBN: 0849383471 Author: John G. Webster Publisher: CRC Press Edition: (December 29, 1998) Pages: 2608 pages URL: http://www.amazon.com/exec/obidos/redirect?tag=songstech-20&path=ASIN%2F0849383471 Summary: The Measurement Instrumentation and Sensors Handbook describes the use of instruments and techniques for practical measurements required in engineering, physics, chemistry, and the life sciences.The book examines: oSensors oHardware oSoftware oTechniques oInformation processing systems oAutomatic data acquisition oReduction and analysis as well as their incorporation for control purposes Organized according to the measurement problem, each section addresses the different ways of making a measurement for a given variable. Chapters present information on three levels: oBasic information without equations and a description of the subject that can be understood by the newcomer oDetailed text and mathematical treatment essential for discovering applications and solving problems outside one's field of specialty oAdvanced applications of the subject, evaluative opinions, and areas for future study The Measurement, Instrumentation and Sensors Handbook provides a graded level of difficulty from start to finish, serving the reference needs of the broadest group of readers. Edited by one of the more noted instrumentation experts in the world, the book contains nearly 150 contributions, covering all aspects on the design and implementation of various instrumentation. ~ Bioelectronics Medicine, chemistry, physics and engineering stand poised to benefit within the next few years from the ingenuity of complex biological structures invented and perfected by nature over millions of years. The combination of biological elements -- be it whole cells, single molecules or anything in between -- with the field of inorganic electronics yields a fascinating spectrum of opportunities and potential applications. Neurons, DNA strands, antigens, antibodies or enzymes connected to conventional circuitry are capable of turning biological activity into defined electrical signals which can be interpreted and acted upon, opening up such applications as bio- and immunosensors, neuronal or DNA computing, bioassays, or biochemical batteries. Similarly, sophisticated human/machine interfaces and ecologically benign harvesting of energy are equally attractive paths awaiting exploration. This book provides both researchers and engineers as well as students of all the natural sciences a vivid insight into the world of bioelectronics and nature's own nanotechnological treasure chamber ~ Biomaterials Science: An Introduction to Materials in Medicine Author: Buddy D. Ratner (Editor), Fredenck J. Scheon (Editor), Allan S. Hoffman Editor Edition: July, 1996 Hardcover: 484 pages This book introduces a subject that has profound impact on human health and considerable economic importance. The issues addressed include the biology, medical applications, markets, regulation, and ethical issues involved in biomaterials science. This spectrum of issues reflects the interdisciplinary nature of the field Key Features * Provides a strong, cohesive compilation unlike any other currently on the market * Covers the entire spectrum of biomaterials and their use in medicine * Contributions of leaders in the biomaterials field ~ Handbook of Medical Imaging Processing and Analysis In recent years, the remarkable advances in medical imaging instruments have increased their use considerably for diagnostics as well as planning and follow-up of treatment. Emerging from the fields of radiology, medical physics and engineering, medical imaging no longer simply deals with the technology and interpretation of radiographic images. The limitless possibilities presented by computer science and technology, coupled with engineering advances in signal processing, optics and nuclear medicine have created the vastly expanded field of medical imaging. The Handbook of Medical Imaging is the first comprehensive compilation of the concepts and techniques used to analyze and manipulate medical images after they have been generated or digitized. The Handbook is organized in six sections that relate to the main functions needed for processing: enhancement, segmentation, quantification, registration, visualization as well as compression storage and telemedicine. * Internationally renowned authors(Johns Hopkins, Harvard, UCLA, Yale, Columbia, UCSF) * Includes imaging and visualization * Contains over 60 pages of stunning, four-color images |